Conserved Amblyomma americanum tick Serpin19, an inhibitor of blood clotting factors Xa and XIa, trypsin and plasmin, has anti-haemostatic functions

Tick saliva serine protease inhibitors (serpins) facilitate tick blood meal feeding through inhibition of protease mediators of host defense pathways. We previously identified a highly conserved Amblyomma americanum serpin (AAS) 19 that is characterized by its reactive center loop being 100% conserv...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Parasitol
Hauptverfasser: Kim, Tae Kwon, Tirloni, Lucas, Radulovic, Zeljko, Lewis, Lauren, Bakshi, Mariam, Hill, Creston, Vaz, Itabajara da Silva, Logullo, Carlos, Termignoni, Carlos, Mulenga, Albert
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490099/
https://ncbi.nlm.nih.gov/pubmed/25957161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpara.2015.03.009
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