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Balancing Proliferation and Connectivity in PTEN-associated Autism Spectrum Disorder

Germline mutations in PTEN, which encodes a widely expressed phosphatase, was mapped to 10q23 and identified as the susceptibility gene for Cowden syndrome, characterized by macrocephaly and high risks of breast, thyroid, and other cancers. The phenotypic spectrum of PTEN mutations expanded to inclu...

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Publicat a:Neurotherapeutics
Autors principals: Tilot, Amanda K., Frazier, Thomas W., Eng, Charis
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489960/
https://ncbi.nlm.nih.gov/pubmed/25916396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-015-0356-8
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