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Differential regulation of monocyte cytokine release by αV and β(2) integrins that bind CD23

The human soluble CD23 (sCD23) protein displays highly pleiotropic cytokine-like activity. Monocytic cells express the sCD23-binding integrins αVβ(3), αVβ(5), αMβ(2) and αXβ(2), but it is unclear which of these four integrins most acutely regulates sCD23-driven cytokine release. The hypothesis that...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Edkins, Adrienne L, Borland, Gillian, Acharya, Mridu, Cogdell, Richard J, Ozanne, Bradford W, Cushley, William
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489923/
https://ncbi.nlm.nih.gov/pubmed/22348662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2012.03576.x
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