Blockade of the N-Methyl-D-Aspartate Glutamate Receptor Ameliorates Lipopolysaccharide-Induced Renal Insufficiency

N-methyl-D-aspartate (NMDA) receptor activation in rat kidney reduces renal perfusion and ultrafiltration. Hypoperfusion-induced ischemia is the most frequent cause of functional insufficiency in the endotoxemic kidney. Here, we used non-hypotensive rat model of lipopolysaccharide-induced endotoxemi...

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Publicat a:PLoS One
Autors principals: Lin, Chian-Shiung, Hung, Shun-Fa, Huang, Ho-Shiang, Ma, Ming-Chieh
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489897/
https://ncbi.nlm.nih.gov/pubmed/26133372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132204
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