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In Vivo Profiling Reveals a Competent Heat Shock Response in Adult Neurons: Implications for Neurodegenerative Disorders

The heat shock response (HSR) is the main pathway used by cells to counteract proteotoxicity. The inability of differentiated neurons to induce an HSR has been documented in primary neuronal cultures and has been proposed to play a critical role in ageing and neurodegeneration. However, this accepte...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Carnemolla, Alisia, Lazell, Hayley, Moussaoui, Saliha, Bates, Gillian P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489736/
https://ncbi.nlm.nih.gov/pubmed/26134141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131985
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