α(2)-Macroglobulin Can Crosslink Multiple Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Molecules and May Facilitate Adhesion of Parasitized Erythrocytes

Rosetting, the adhesion of Plasmodium falciparum-infected erythrocytes to uninfected erythrocytes, involves clonal variants of the parasite protein P. falciparum erythrocyte membrane protein 1 (PfEMP1) and soluble serum factors. While rosetting is a well-known phenotypic marker of parasites associat...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Stevenson, Liz, Laursen, Erik, Cowan, Graeme J., Bandoh, Betty, Barfod, Lea, Cavanagh, David R., Andersen, Gregers R., Hviid, Lars
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489720/
https://ncbi.nlm.nih.gov/pubmed/26134405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005022
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