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A Fine Balance of Dietary Lipids Improves Pathology of a Murine Model of VCP-Associated Multisystem Proteinopathy

The discovery of effective therapies and of disease mechanisms underlying valosin containing protein (VCP)-associated myopathies and neurodegenerative disorders remains elusive. VCP disease, caused by mutations in the VCP gene, are a clinically and genetically heterogeneous group of disorders with m...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Llewellyn, Katrina J., Walker, Naomi, Nguyen, Christopher, Tan, Baichang, BenMohamed, Lbachir, Kimonis, Virginia E., Nalbandian, Angèle
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489713/
https://ncbi.nlm.nih.gov/pubmed/26134519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131995
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