Esophageal epithelial cells acquire functional characteristics of activated myofibroblasts after undergoing an epithelial to mesenchymal transition

BACKGROUND AND AIMS: Eosinophilic esophagitis (EoE) is an allergic inflammatory disease that leads to esophageal fibrosis and stricture. We have recently shown that in EoE, esophageal epithelial cells undergo an epithelial to mesenchymal transition (EMT), characterized by gain of mesenchymal markers...

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Detalhes bibliográficos
Publicado no:Exp Cell Res
Main Authors: Muir, Amanda B., Dods, Kara, Noah, Yuli, Toltzis, Sarit, Chandramouleeswaran, Prasanna Modayur, Lee, Anna, Benitez, Alain, Bedenbaugh, Adam, Falk, Gary W., Wells, Rebecca G., Nakagawa, Hiroshi, Wang, Mei-Lun
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489692/
https://ncbi.nlm.nih.gov/pubmed/25183431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2014.08.026
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