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Low Copy Number of the AMY1 Locus Is Associated with Early-Onset Female Obesity in Finland

BACKGROUND: The salivary α-amylase locus (AMY1) is located in a highly polymorphic multi allelic copy number variable chromosomal region. A recent report identified an association between AMY1 copy numbers and BMI in common obesity. The present study investigated the relationship between AMY1 copy n...

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Veröffentlicht in:PLoS One
Hauptverfasser: Viljakainen, Heli, Andersson-Assarsson, Johanna C, Armenio, Miriam, Pekkinen, Minna, Pettersson, Maria, Valta, Helena, Lipsanen-Nyman, Marita, Mäkitie, Outi, Lindstrand, Anna
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489572/
https://ncbi.nlm.nih.gov/pubmed/26132294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131883
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