The efficacy of 2-nitrovinylfuran derivatives against Leishmania in vitro and in vivo

Despite recent advances in the treatment of some forms of leishmaniasis, the available drugs are still far from ideal due to inefficacy, parasite resistance, toxicity and cost. The wide-spectrum antimicrobial activity of 2-nitrovinylfuran compounds has been described, as has their activity against T...

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Udgivet i:Mem Inst Oswaldo Cruz
Main Authors: Sifontes-Rodríguez, Sergio, Monzote-Fidalgo, Lianet, Castañedo-Cancio, Nilo, Montalvo-Álvarez, Ana Margarita, López-Hernández, Yamilé, Diogo, Niurka Mollineda, Infante-Bourzac, Juan Francisco, Pérez-Martín, Oliver, Meneses-Marcel, Alfredo, García-Trevijano, José Antonio Escario, Cabrera-Pérez, Miguel Ángel
Format: Artigo
Sprog:Inglês
Udgivet: Instituto Oswaldo Cruz, Ministério da Saúde 2015
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489446/
https://ncbi.nlm.nih.gov/pubmed/25946239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-02760140324
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