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Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis
INTRODUCTION: Microglia are tissue macrophages of the central nervous system that monitor brain homeostasis and react upon neuronal damage and stress. Aging and neurodegeneration induce a hypersensitive, pro-inflammatory phenotype, referred to as primed microglia. To determine the gene expression si...
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Yayımlandı: | Acta Neuropathol Commun |
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Asıl Yazarlar: | , , , , , , , , , , , , |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
BioMed Central
2015
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4489356/ https://ncbi.nlm.nih.gov/pubmed/26001565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-015-0203-5 |
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