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ENCoM server: exploring protein conformational space and the effect of mutations on protein function and stability

ENCoM is a coarse-grained normal mode analysis method recently introduced that unlike previous such methods is unique in that it accounts for the nature of amino acids. The inclusion of this layer of information was shown to improve conformational space sampling and apply for the first time a coarse...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Frappier, Vincent, Chartier, Matthieu, Najmanovich, Rafael J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489264/
https://ncbi.nlm.nih.gov/pubmed/25883149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv343
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