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Significance of filamin A in mTORC2 function in glioblastoma

BACKGROUND: Glioblastoma multiforme (GBM) is one of the most highly metastatic cancers. GBM has been associated with a high level of the mechanistic target of rapamycin complex 2 (mTORC2) activity. We aimed to observe roles of mTORC2 in GBM cells especially on actin cytoskeleton reorganization, cell...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Chantaravisoot, Naphat, Wongkongkathep, Piriya, Loo, Joseph A., Mischel, Paul S., Tamanoi, Fuyuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4489161/
https://ncbi.nlm.nih.gov/pubmed/26134617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0396-z
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