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FOXL2 modulates cartilage, skeletal development and IGF1-dependent growth in mice
BACKGROUND: Haploinsufficiency of the FOXL2 transcription factor in humans causes Blepharophimosis/Ptosis/Epicanthus Inversus syndrome (BPES), characterized by eyelid anomalies and premature ovarian failure. Mice lacking Foxl2 recapitulate human eyelid/forehead defects and undergo female gonadal dys...
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| Publicado no: | BMC Dev Biol |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4489133/ https://ncbi.nlm.nih.gov/pubmed/26134413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12861-015-0072-y |
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