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Toxicity of myristic acid analogs toward African trypanosomes.

New drugs are needed for treatment of diseases caused by African trypanosomes. One possible target for chemotherapy is the biosynthesis of the glycosyl phosphatidyl-inositol (GPI) of this parasite's variant surface glycoprotein (VSG). Unlike mammalian GPIs, the diacylglycerol moiety of the VSG ancho...

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Foilsithe in:Proc Natl Acad Sci U S A
Príomhchruthaitheoirí: Doering, T L, Lu, T, Werbovetz, K A, Gokel, G W, Hart, G W, Gordon, J I, Englund, P T
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: National Academy of Sciences 1994
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44891/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937882/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.21.9735
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