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In Vivo Protective Effects of Diosgenin against Doxorubicin-Induced Cardiotoxicity

Doxorubicin (DOX) induces oxidative stress leading to cardiotoxicity. Diosgenin, a steroidal saponin of Dioscorea opposita, has been reported to have antioxidant activity. Our study was aimed to find out the protective effect of diosgenin against DOX-induced cardiotoxicity in mice. DOX treatment led...

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Detalhes bibliográficos
Publicado no:Nutrients
Main Authors: Chen, Chih-Tai, Wang, Zhi-Hong, Hsu, Cheng-Chin, Lin, Hui-Hsuan, Chen, Jing-Hsien
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488824/
https://ncbi.nlm.nih.gov/pubmed/26091236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu7064938
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