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Proteasome as a Molecular Target of Microcystin-LR
Proteasome degrades proteins in eukaryotic cells. As such, the proteasome is crucial in cell cycle and function. This study proved that microcystin-LR (MC-LR), which is a toxic by-product of algal bloom, can target cellular proteasome and selectively inhibit proteasome trypsin-like (TL) activity. MC...
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Udgivet i: | Toxins (Basel) |
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Main Authors: | , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
MDPI
2015
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4488699/ https://ncbi.nlm.nih.gov/pubmed/26090622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins7062221 |
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