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Proteasome as a Molecular Target of Microcystin-LR

Proteasome degrades proteins in eukaryotic cells. As such, the proteasome is crucial in cell cycle and function. This study proved that microcystin-LR (MC-LR), which is a toxic by-product of algal bloom, can target cellular proteasome and selectively inhibit proteasome trypsin-like (TL) activity. MC...

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Bibliografiske detaljer
Udgivet i:Toxins (Basel)
Main Authors: Zhu, Zhu, Zhang, Li, Shi, Guoqing
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488699/
https://ncbi.nlm.nih.gov/pubmed/26090622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins7062221
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