The Discovery of Novel Biomarkers Improves Breast Cancer Intrinsic Subtype Prediction and Reconciles the Labels in the METABRIC Data Set

BACKGROUND: The prediction of breast cancer intrinsic subtypes has been introduced as a valuable strategy to determine patient diagnosis and prognosis, and therapy response. The PAM50 method, based on the expression levels of 50 genes, uses a single sample predictor model to assign subtype labels to...

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Publicat a:PLoS One
Autors principals: Milioli, Heloisa Helena, Vimieiro, Renato, Riveros, Carlos, Tishchenko, Inna, Berretta, Regina, Moscato, Pablo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488510/
https://ncbi.nlm.nih.gov/pubmed/26132585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129711
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