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The Low-Cost Compound Lignosulfonic Acid (LA) Exhibits Broad-Spectrum Anti-HIV and Anti-HSV Activity and Has Potential for Microbicidal Applications

OBJECTIVES: Lignosulfonic acid (LA), a low-cost lignin-derived polyanionic macromolecule, was extensively studied for its anti-HIV and anti-HSV activity in various cellular assays, its mechanism of viral inhibition and safety profile as potential microbicide. RESULTS: LA demonstrated potent inhibito...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gordts, Stephanie C., Férir, Geoffrey, D’huys, Thomas, Petrova, Mariya I., Lebeer, Sarah, Snoeck, Robert, Andrei, Graciela, Schols, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488490/
https://ncbi.nlm.nih.gov/pubmed/26132818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131219
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