Emodin Inhibits Homocysteine-Induced C-Reactive Protein Generation in Vascular Smooth Muscle Cells by Regulating PPARγ Expression and ROS-ERK1/2/p38 Signal Pathway

Atherosclerosis is an inflammatory disease. As an inflammatory molecule, C-reactive protein (CRP) plays a direct role in atherogenesis. It is known that the elevated plasma homocysteine (Hcy) level is an independent risk factor for atherosclerosis. We previously reported that Hcy produces a pro-infl...

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Bibliographic Details
Published in:PLoS One
Main Authors: Pang, Xiaoming, Liu, Juntian, Li, Yuxia, Zhao, Jingjing, Zhang, Xiaolu
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488440/
https://ncbi.nlm.nih.gov/pubmed/26131983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131295
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