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Are Changes in Composition in Response to Treatment of a Mouse Model of Osteogenesis Imperfecta Sex-dependent?

BACKGROUND: Osteogenesis imperfecta (OI) is a genetic disease characterized by skeletal fragility and deformity. There is extensive debate regarding treatment options in adults with OI. Antiresorptive treatment reduces the number of fractures in growing oim/oim mice, an animal model that reproducibl...

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Pubblicato in:Clin Orthop Relat Res
Autori principali: Boskey, Adele L., Marino, Josephine, Spevak, Lyudmila, Pleshko, Nancy, Doty, Stephen, Carter, Erin M., Raggio, Cathleen L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488219/
https://ncbi.nlm.nih.gov/pubmed/25903941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-015-4268-z
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