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Uncovering correlated variability in epigenomic datasets using the Karhunen-Loeve transform

BACKGROUND: Larger variation exists in epigenomes than in genomes, as a single genome shapes the identity of multiple cell types. With the advent of next-generation sequencing, one of the key problems in computational epigenomics is the poor understanding of correlations and quantitative differences...

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Detalhes bibliográficos
Publicado no:BioData Min
Main Authors: Madrigal, Pedro, Krajewski, Paweł
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4488123/
https://ncbi.nlm.nih.gov/pubmed/26140054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13040-015-0051-7
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