Surface topography induces 3D self-orientation of cells and extracellular matrix resulting in improved tissue function

The organization of cells and extracellular matrix (ECM) in native tissues plays a crucial role in their functionality. However, in tissue engineering, cells and ECM are randomly distributed within a scaffold. Thus, the production of engineered-tissue with complex 3D organization remains a challenge...

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Bibliografiske detaljer
Udgivet i:Integr Biol (Camb)
Main Authors: Guillemette, Maxime D., Cui, Bo, Roy, Emmanuel, Gauvin, Robert, Giasson, Claude J., Esch, Mandy B., Carrier, Patrick, Deschambeault, Alexandre, Dumoulin, Michel, Toner, Mehmet, Germain, Lucie, Veres, Teodor, Auger, Francois A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487987/
https://ncbi.nlm.nih.gov/pubmed/20023803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b820208g
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