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A self-assembling peptide matrix used to control stiffness and binding site density supports the formation of microvascular networks in three dimensions

A three-dimensional (3-D) cell culture system that allows control of both substrate stiffness and integrin binding density was created and characterized. This system consisted of two self-assembling peptide (SAP) sequences that were mixed in different ratios to achieve the desired gel stiffness and...

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Detalhes bibliográficos
Publicado no:Acta Biomater
Main Authors: Stevenson, M.D., Piristine, H., Hogrebe, N.J., Nocera, T.M., Boehm, M.W., Reen, R.K., Koelling, K.W., Agarwal, G., Sarang-Sieminski, A.L., Gooch, K.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487911/
https://ncbi.nlm.nih.gov/pubmed/23603000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2013.04.002
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