The P-loop region of Schlafen 3 acts within the cytosol to induce differentiation of human Caco-2 intestinal epithelial cells

Schlafen 3 (Slfn3) mediates rodent enterocyte differentiation in vitro and in vivo, required for intestinal function. Little is known about Schlafen protein structure-function relationships. To define the Slfn3 domain that promotes differentiation, we studied villin and sucrase isomaltase (SI) promo...

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Pubblicato in:Biochim Biophys Acta
Autori principali: Chaturvedi, Lakshmishankar, Sun, Kelian, Walsh, Mary F., Kuhn, Leslie A., Basson, Marc D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487865/
https://ncbi.nlm.nih.gov/pubmed/25261706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.09.017
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