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ERK1 and ERK2 regulate chondrocyte terminal differentiation during endochondral bone formation
Chondrocytes in the epiphyseal cartilage undergo terminal differentiation prior to their removal through apoptosis. To examine the role of ERK1 and ERK2 in chondrocyte terminal differentiation, we generated Osx-Cre; ERK1(−/−); ERK2(flox/flox) mice (cKO(osx)), in which ERK1 and ERK2 were deleted in h...
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| Udgivet i: | J Bone Miner Res |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4487783/ https://ncbi.nlm.nih.gov/pubmed/25401279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2409 |
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