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EFTUD2 deficiency in vertebrates: identification of a novel human mutation and generation of a zebrafish model

BACKGROUND: Congenital microphthalmia and coloboma are severe developmental defects that are frequently associated with additional systemic anomalies and display a high level of genetic heterogeneity. METHODS: To identify the pathogenic variant in a patient with microphthalmia, coloboma, retinal dys...

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Vydáno v:Birth Defects Res A Clin Mol Teratol
Hlavní autoři: Deml, Brett, Reis, Linda M., Muheisen, Sanaa, Bick, David, Semina, Elena V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487781/
https://ncbi.nlm.nih.gov/pubmed/26118977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdra.23397
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