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A Mutation-Sensitive Switch Assay to Detect Five Clinically Significant Epidermal Growth Factor Receptor Mutations

Epidermal growth factor receptor (EGFR) mutations can affect the therapeutic efficacy of drugs used to treat nonsmall-cell lung cancer (NSCLC). We aimed to develop methods to detect five common EGFR somatic mutations in tumor tissues from NSCLC patients by using a nanoscale mutation-sensitive switch...

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Detalhes bibliográficos
Publicado no:Genet Test Mol Biomarkers
Main Authors: Liu, Bin, Zhou, Lin, Wang, Qian, Li, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487682/
https://ncbi.nlm.nih.gov/pubmed/25918867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/gtmb.2014.0329
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