The cancer glycocalyx mechanically primes integrin-mediated growth and survival

Malignancy is associated with altered expression of glycans and glycoproteins that contribute to the cellular glycocalyx. We constructed a glycoprotein expression signature, which revealed that metastatic tumours upregulate expression of bulky glycoproteins. A computational model predicted that thes...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nature
मुख्य लेखकों: Paszek, Matthew J., DuFort, Christopher C., Rossier, Olivier, Bainer, Russell, Mouw, Janna K., Godula, Kamil, Hudak, Jason E., Lakins, Jonathon N., Wijekoon, Amanda C., Cassereau, Luke, Rubashkin, Matthew G., Magbanua, Mark J., Thorn, Kurt S., Davidson, Michael W., Rugo, Hope S., Park, John W., Hammer, Daniel A., Giannone, Grégory, Bertozzi, Carolyn R., Weaver, Valerie M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487551/
https://ncbi.nlm.nih.gov/pubmed/25030168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13535
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