Dual regulation of Ca2+/calmodulin-dependent kinase II activity by membrane voltage and by calcium influx.

Calcium entry through voltage-gated Ca2+ channels is critical in cardiac excitation-contraction coupling and calcium metabolism. In this report, we demonstrate both spatially resolved and temporally distinct effects of Ca2+/calmodulin-dependent protein kinase II (CaMKII) on L-type Ca2+ channel curre...

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Autors principals: Xiao, R P, Cheng, H, Lederer, W J, Suzuki, T, Lakatta, E G
Format: Artigo
Idioma:Inglês
Publicat: 1994
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC44873/
https://ncbi.nlm.nih.gov/pubmed/7937825
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