Functional BCL-2 regulatory genetic variants contribute to susceptibility of esophageal squamous cell carcinoma

B-cell lymphoma-2 (BCL-2) prevents apoptosis and its overexpression could promote cancer cell survival. Multiple functional BCL-2 genetic polymorphisms, such as rs2279115, rs1801018 and rs1564483, have been identified previously and might be involved in cancer development through deregulating BCL-2...

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Publicado no:Sci Rep
Main Authors: Pan, Wenting, Yang, Jinyun, Wei, Jinyu, Chen, Hongwei, Ge, Yunxia, Zhang, Jingfeng, Wang, Zhiqiong, Zhou, Changchun, Yuan, Qipeng, Zhou, Liqing, Yang, Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487241/
https://ncbi.nlm.nih.gov/pubmed/26132559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11833
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