CAPON Modulates Neuronal Calcium Handling and Cardiac Sympathetic Neurotransmission During Dysautonomia in Hypertension

Genome-wide association studies implicate a variant in the neuronal nitric oxide synthase adaptor protein (CAPON) in electrocardiographic QT variation and sudden cardiac death. Interestingly, nitric oxide generated by neuronal NO synthase-1 reduces norepinephrine release; however, this pathway is do...

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Publicado en:Hypertension
Autores principales: Lu, Chieh-Ju, Hao, Guoliang, Nikiforova, Natalia, Larsen, Hege E., Liu, Kun, Crabtree, Mark J., Li, Dan, Herring, Neil, Paterson, David J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487208/
https://ncbi.nlm.nih.gov/pubmed/25916729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.05290
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