Nitric oxide/cyclic guanosine monophosphate inducers sodium nitroprusside and L-arginine inhibit the proliferation of gastric cancer cells via the activation of type II cyclic guanosine monophosphate-dependent protein kinase

Nitric oxide (NO) may activate soluble guanylyl cyclase (sGC), resulting in the increase of intracellular cyclic guanosine monophosphate (cGMP), a key molecule in the activation of type II cGMP-dependent protein kinase (PKG II). In our previous study, the membrane-permeable cGMP analogue 8-pCPT-cGMP...

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Publié dans:Oncol Lett
Auteurs principaux: YAO, XIAOYUAN, WU, YAN, ZHU, MIAOLIN, QIAN, HAI, CHEN, YONGCHANG
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2015
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487134/
https://ncbi.nlm.nih.gov/pubmed/26171055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.3229
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