Type II cyclic guanosine monophosphate-dependent protein kinase inhibits Rac1 activation in gastric cancer cells

Enhanced motility of cancer cells is a critical step in promoting tumor metastasis, which remains the major cause of gastric cancer-associated mortality. The small GTPase Rac1 is a key signaling component in the regulation of cell migration. Previous studies have demonstrated that Rac1 activity may...

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Publicado en:Oncol Lett
Autores principales: WANG, YING, CHEN, YONGCHANG, WU, MIN, LAN, TING, WU, YAN, LI, YUEYING, QIAN, HAI
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2015
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487129/
https://ncbi.nlm.nih.gov/pubmed/26171059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2015.3173
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