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Mechanisms of recognition and binding of α-TTP to the plasma membrane by multi-scale molecular dynamics simulations

We used multiple sets of simulations both at the atomistic and coarse-grained level of resolution to investigate interaction and binding of α-tochoperol transfer protein (α-TTP) to phosphatidylinositol phosphate lipids (PIPs). Our calculations indicate that enrichment of membranes with such lipids f...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Lamprakis, Christos, Stocker, Achim, Cascella, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4487086/
https://ncbi.nlm.nih.gov/pubmed/26191529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2015.00036
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