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Calmodulin as a major calcium buffer shaping vesicular release and short-term synaptic plasticity: facilitation through buffer dislocation

Action potential-dependent release of synaptic vesicles and short-term synaptic plasticity are dynamically regulated by the endogenous Ca(2+) buffers that shape [Ca(2+)] profiles within a presynaptic bouton. Calmodulin is one of the most abundant presynaptic proteins and it binds Ca(2+) faster than...

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Pubblicato in:Front Cell Neurosci
Autori principali: Timofeeva, Yulia, Volynski, Kirill E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486835/
https://ncbi.nlm.nih.gov/pubmed/26190970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00239
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