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Interferon-β and temozolomide combination therapy for temozolomide monotherapy-refractory malignant gliomas

Interferon-β (IFN-β) has been found to downregulate O(6)-methyl-guanine-DNA methyltransferase and sensitize glioma cells to chemoradiation therapy. The effectiveness of IFN-β and temozolomide (TMZ) combination therapy for newly diagnosed glioblastomas was previously reported. However, there is no cl...

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Publicado en:Mol Clin Oncol
Autores principales: KAWAJI, HIROSHI, TOKUYAMA, TSUTOMU, YAMASAKI, TOMOHIRO, AMANO, SHINJI, SAKAI, NAOTO, NAMBA, HIROKI
Formato: Artigo
Lenguaje:Inglês
Publicado: D.A. Spandidos 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486788/
https://ncbi.nlm.nih.gov/pubmed/26171205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2015.542
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