White matter tract oriented deformation predicts traumatic axonal brain injury and reveals rotational direction-specific vulnerabilities

A systematic correlation between finite element models (FEMs) and histopathology is needed to define deformation thresholds associated with traumatic brain injury (TBI). In this study, a FEM of a transected piglet brain was used to reverse engineer the range of optimal shear moduli for infant (5-day...

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Veröffentlicht in:Biomech Model Mechanobiol
Hauptverfasser: Sullivan, Sarah, Eucker, Stephanie A., Gabrieli, David, Bradfield, Connor, Coats, Brittany, Maltese, Matthew R., Lee, Jongho, Smith, Colin, Margulies, Susan S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486640/
https://ncbi.nlm.nih.gov/pubmed/25547650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-014-0643-z
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