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Elevated Intracranial Pressure and Cerebral Edema following Permanent MCA Occlusion in an Ovine Model

INTRODUCTION: Malignant middle cerebral artery (MCA) stroke has a disproportionately high mortality due to the rapid development of refractory space-occupying cerebral edema. Animal models are essential in developing successful anti-edema therapies; however to date poor clinical translation has been...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Wells, Adam J., Vink, Robert, Helps, Stephen C., Knox, Steven J., Blumbergs, Peter C., Turner, Renée J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486455/
https://ncbi.nlm.nih.gov/pubmed/26121036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0130512
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