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ROS-p53-cyclophilin-D signaling mediates salinomycin-induced glioma cell necrosis
BACKGROUND: The primary glioblastoma multiforme (GBM) is the most malignant form of astrocytic tumor with an average survival of approximately 12–14 months. The search for novel and more efficient chemo-agents against this disease is urgent. Salinomycin induces broad anti-cancer effects; however, it...
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| Published in: | J Exp Clin Cancer Res |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4486428/ https://ncbi.nlm.nih.gov/pubmed/26024660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0174-1 |
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