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Integrated approaches to miRNAs target definition: time-series analysis in an osteosarcoma differentiative model

BACKGROUND: microRNAs (miRs) are small non-coding RNAs involved in the fine regulation of several cellular processes by inhibiting their target genes at post-transcriptional level. Osteosarcoma (OS) is a tumor thought to be related to a molecular blockade of the normal process of osteoblast differen...

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Bibliographische Detailangaben
Veröffentlicht in:BMC Med Genomics
Hauptverfasser: Grilli, A., Sciandra, M., Terracciano, M., Picci, P., Scotlandi, K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4486310/
https://ncbi.nlm.nih.gov/pubmed/26123714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-015-0106-0
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