Identification of prosaposin as a neurotrophic factor.

Prosaposin was identified as a neurotrophic factor stimulating neurite outgrowth in murine neuroblastoma (NS20Y) cells and choline acetyltransferase (ChAT) activity in human neuroblastoma (SK-N-MC) cells. The four naturally occurring saposins, which are derived by proteolytic processing of prosaposi...

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Bibliographic Details
Main Authors: O'Brien, J S, Carson, G S, Seo, H C, Hiraiwa, M, Kishimoto, Y
Format: Artigo
Language:Inglês
Published: 1994
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC44859/
https://ncbi.nlm.nih.gov/pubmed/7937812
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