Kick-starting the cancer-immunity cycle by targeting CD40

Stimulation of CD40 on dendritic cells to expand and activate tumor-specific T cells and generate anticancer immunity is an attractive therapeutic approach. Since CD40 agonists exert their effects upstream of checkpoint inhibitors, including PD-1 or PD-L1 antagonists, they are ideal candidates for c...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Ellmark, P, Mangsbo, S M, Furebring, C, Tötterman, T H, Norlén, P
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485842/
https://ncbi.nlm.nih.gov/pubmed/26140231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1011484
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