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Combinatorial immunotherapy with checkpoint blockers solves the problem of metastatic melanoma—An exclamation sign with a question mark

Results from recent clinical trials demonstrate that a combinatorial immunotherapeutic regimen based on 2 distinct checkpoint blockers, namely, the CTLA4-targeting agent ipilimumab and the PD-1-specific molecule nivolumab, causes objective responses in a majority of subjects with advanced melanoma....

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Publicat a:Oncoimmunology
Autors principals: Kroemer, Guido, Galluzzi, Lorenzo
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485790/
https://ncbi.nlm.nih.gov/pubmed/26140249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1058037
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