Repeated intratumoral administration of ONCOS-102 leads to systemic antitumor CD8(+) T-cell response and robust cellular and transcriptional immune activation at tumor site in a patient with ovarian cancer

Adenoviruses are excellent immunotherapeutic agents with a unique ability to prime and boost immune responses. Recombinant adenoviruses cause immunogenic cancer cell death and subsequent release of tumor antigens for antigen presenting cells, resulting in the priming of potent tumor-specific immunit...

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書目詳細資料
發表在:Oncoimmunology
Main Authors: Vassilev, L, Ranki, T, Joensuu, T, Jäger, E, Karbach, J, Wahle, C, Partanen, K, Kairemo, K, Alanko, T, Turkki, R, Linder, N, Lundin, J, Ristimäki, A, Kankainen, M, Hemminki, A, Backman, C, Dienel, K, von Euler, M, Haavisto, E, Hakonen, T, Juhila, J, Jäderberg, M, Priha, P, Vuolanto, A, Pesonen, S
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2015
主題:
Brief Report
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485730/
https://ncbi.nlm.nih.gov/pubmed/26140248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1017702
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