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A novel approach to detect KRAS/BRAF mutation for colon cancer: Highly sensitive simultaneous detection of mutations and simple pre-treatment without DNA extraction

It has been reported that colon cancer patients with KRAS and BRAF mutations that lie downstream of epidermal growth factor receptor (EGFR) acquire resistance against therapy with anti-EGFR antibodies, cetuximab and panitumumab. On the other hand, some reports say KRAS codon 13 mutation (p.G13D) has...

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Detalhes bibliográficos
Publicado no:Int J Oncol
Main Authors: SUZUKI, SHUN-ICHI, MATSUSAKA, SATOSHI, HIRAI, MITSUHARU, SHIBATA, HARUMI, TAKAGI, KOICHI, MIZUNUMA, NOBUYUKI, HATAKE, KIYOHIKO
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485654/
https://ncbi.nlm.nih.gov/pubmed/25936694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2015.2978
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