Custom fractional factorial designs to develop atorvastatin self-nanoemulsifying and nanosuspension delivery systems – enhancement of oral bioavailability

Poor water solubility of a drug is a major challenge in drug delivery research and a main cause for limited bioavailability and pharmacokinetic parameters. This work aims to utilize custom fractional factorial design to assess the development of self-nanoemulsifying drug delivery systems (SNEDDS) an...

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Enregistré dans:
Détails bibliographiques
Publié dans:Drug Des Devel Ther
Auteurs principaux: Hashem, Fahima M, Al-Sawahli, Majid M, Nasr, Mohamed, Ahmed, Osama AA
Format: Artigo
Langue:Inglês
Publié: Dove Medical Press 2015
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485649/
https://ncbi.nlm.nih.gov/pubmed/26150693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S86126
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