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Disease-Associated SNPs From non-Coding Regions in Juvenile Idiopathic Arthritis Are Located Within or Adjacent to Functional Genomic Elements of Human Neutrophils and CD4+ T Cells

BACKGROUND: Juvenile idiopathic arthritis (JIA) is considered a complex trait in which the environment interacts with inherited genes to produce a phenotype that shows broad inter-individual variance. A recently completed genome-wide association study (GWAS) identified 24 regions of genetic risk for...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Jiang, Kaiyu, Zhu, Lisha, Buck, Michael J., Chen, Yanmin, Carrier, Bradley, Liu, Tao, Jarvis, James N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485537/
https://ncbi.nlm.nih.gov/pubmed/25833190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39135
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