Exogenous 17-β estradiol administration blunts progression of established angiotensin II-induced abdominal aortic aneurysms in female ovariectomized mice

BACKGROUND: Abdominal aortic aneurysms (AAAs) occur predominately in males. However, AAAs in females have rapid growth rates and rupture at smaller sizes. Mechanisms contributing to AAA progression in females are undefined. We defined effects of ovariectomy, with and without 17-β estradiol (E2), on...

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Detalhes bibliográficos
Publicado no:Biol Sex Differ
Main Authors: Thatcher, Sean E., Zhang, Xuan, Woody, Shannon, Wang, Yu, Alsiraj, Yasir, Charnigo, Richard, Daugherty, Alan, Cassis, Lisa A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485333/
https://ncbi.nlm.nih.gov/pubmed/26131353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13293-015-0030-1
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