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A novel embryonic plasticity gene signature that predicts metastatic competence and clinical outcome

Currently, very few prognosticators accurately predict metastasis in cancer patients. In order to complete the metastatic cascade and successfully colonize distant sites, carcinoma cells undergo dynamic epithelial-mesenchymal-transition (EMT) and its reversal, mesenchymal-epithelial-transition (MET)...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Soundararajan, Rama, Paranjape, Anurag N., Barsan, Valentin, Chang, Jeffrey T., Mani, Sendurai A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485318/
https://ncbi.nlm.nih.gov/pubmed/26123483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11766
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